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Structural Bioinformatics

Structural bioinformatics is a subject of bioinformatics dealing with the three-dimensional study and prediction of biological macromolecules like proteins, RNA, and DNA. It uses both empirically solved structures and computer models to generalise macromolecular 3D structures, such as comparisons of overall folds and local motifs, molecular folding principles, evolution, binding interactions, and structure/function correlations. The primary objective of structural bioinformatics is to provide novel methods for analysing biological macromolecular data in order to solve biological problems and discover new information.

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Structural Bioinformatics

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