Proteomics and Genomics

Proteome is the collection of proteins in your body, and proteomics is the study of proteins. After the completion of the Human Genome project, this subject is regarded as one of the major frontiers in biology and personalised medicine.

Proteomics is the application of technology for identifying and quantifying the total protein composition of a cell, tissue, or organism. It supplements other "omics" technologies, including as genomics and transcriptomics, in order to expose the identification of protein of an organism and the structure and activities of a specific protein.

Proteomics-based technologies are utilised in various capacities for various research settings, such as the detection of various diagnostic markers, candidates for vaccine production, the understanding of pathogenicity mechanisms, the modification of expression patterns in response to various signals, and the interpretation of functional protein pathways associated with various diseases. Proteomics is complex since it involves the analysis and classification of overall protein signatures of a genome. Mass spectrometry, with LC–MS-MS and MALDI-TOF/TOF as extensively used instruments, is the central among modern proteomics.

Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment.

Genomics is the study of organisms' whole genomes. It uses some ideas from genetics. Genomics uses recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and study analyse the structure and function of genomes.

Furthermore, genomics focuses on interactions within the genome between loci and alleles, as well as additional interactions such as epistasis, pleiotropy, and heterosis. Genomics takes advantage of the availability of whole DNA sequences for entire organisms, which was made possible by both Fred Sanger's pioneering work and the more recent next-generation sequencing technology. Next-generation sequencing technologies have resulted in dramatic increases in genome sequencing speed, capacity, and affordability. Furthermore, breakthroughs in bioinformatics have permitted the creation of hundreds of life-science databases and programs that promote scientific research.