Macromolecular machines are assemblies with several active sites that facilitate the co-localization and/or coupling of enzymatic activities. Multi-enzyme complexes are a form of macromolecular machine that catalyses sequential chemical processes and is used by many metabolic pathways. For example, yeast fatty acid synthase, is a huge 2 MDa macromolecular machine that assembles into a barrel-shaped particle to enable synthesis via a series of repeated processes. The formation of macromolecular assemblies can be advantageous for metabolic pathways because they can boost catalytic efficiency, safeguard intermediates, and give a high level of control. Ribosome synthesis is a key biological pathway that is dependent on a number of macromolecular machines.
ALSO READ Molecular Biology Structural Biology Folding and Binding Protein Structure Database Protein Engineering Sequence Analysis and Topology 3-D Structure Determination Computational Structural Biology Molecular Modelling and Dynamics Drug Designing and Biomarkers Macromolecular Machines Gene Regulation Cell Signalling Structural Enzymology Structural Bioinformatics Biochemistry and Biophysics Cell Biology Carbohydrate-Protein Interactions and Glycosylation Proteomics and Genomics Structural Biology in Cancer Research Molecular Biology Techniques Advancements in Structural Biology Protein-Nuclic Acid Interactions Membrane Structural Biology Biophysical and Molecular Biological Methods Catalysis and Regulation X-ray Crystallography NMR Spectroscopy cryo-EM Structural Biology in Drug Discovery Structural Biology in Immunology Data Mining in Structural Biology Protein-Protein Interactions Plant Structural Biology Mass Spectrometry in Structural Biology Biomolecular Simulations
Tags
NMR Spectroscopy Conferences
Protein Engineering Conferences
Protein Engineering Conferences
X-ray Crystallography Conferences
Stereochemistry Conferences
Structural Bioinformatics Conferences
Molecular Biology Conferences 2024
Structural Biology Conferences 2024
Genomics Conferences
Structural Genomics Conferences
Molecular Biology Conferences
Computational Structural Biology Conferences
Computational Structural Biology Conferences 2024
Bioinformatics Conferences 2024
Proteomics Conferences