Structural biology research is rapidly growing, and new discoveries are being made at an accelerating pace. The global structural biology and molecular modeling market was valued at USD 2.62 billion in 2020 and is expected to reach USD 3.77 billion by 2025, growing at a compound annual growth rate (CAGR) of 7.5% during the forecast period.
The use of advanced computational techniques, such as machine learning and artificial intelligence, is enabling researchers to analyze complex biological data sets more quickly and accurately than ever before, leading to new insights into the structure and function of biomolecules.
Advances in imaging technologies, such as cryo-electron microscopy, have also revolutionized the field of Structural Biology, allowing researchers to visualize the structures of biological macromolecules in unprecedented detail.
The importance of Structural Biology and Biochemistry in drug discovery and development continues to grow, as researchers seek to identify new drug targets and develop more effective and targeted
about Adv. Structural BIO 2024 conference
Dear participants and esteemed guests,
It gives me great pleasure to extend a warm welcome to the Euro-Global Summit on Advances in Structural Biology and Protein Chemistry which will be held on June 20-21, 2024 Barcelona, Spain.
This conference will bring together leading minds from around the world to share their insights, ideas, and latest findings in molecular biology, structural biology and protein chemistry. It is a unique opportunity to exchange knowledge, explore the frontiers of science, and collaborate with colleagues who share a common passion for innovation and discovery.
Adv. Structural BIO 2024 scientific program consists of state-of-the-art lectures, debates, oral and poster presentations on protein chemistry and structural biology-related topics.
This event will bring together chemists, biotechnologists, structural biologists, molecular biologists, bioinformaticians, pharmaceutical researchers, mathematicians, biologists, computer scientists, statistical researchers, biomedical researchers, and health informaticians in a creative and engaging setting in Barcelona to learn and share their knowledge and views.
It'll be a memorable two-day congress packed with excellent presentations, educational sessions, and cutting-edge lectures from experts from all over the world.
We're looking forward to your participation and deliberation making this congress a roaring success
With best regards,
Adv. Structural BIO 2024
Organizing Committee
Peers Alley Media, Canada
Former Owner of the Advanced Materials Laboratory, Inc, USA
Jinan University, China
University Of Regensburg, Germany
St Francis College, USA
Tags
Molecular Biology Conferences
NMR Spectroscopy Conferences
Proteomics Conferences
Structural Genomics Conferences
Protein Chemistry Conferences
Computational Structural Biology Conferences
cryo-EM Conferences 2024
Proteomics Conferences 2024
Computational Structural Biology Conferences 2024
Protein Engineering Conferences
cryo-EM Conferences
Bioinformatics Conferences
Structural Biology Conferences 2024 USA
Bioinformatics Conferences 2024
X-ray Crystallography Conferences
Tags
NMR Spectroscopy Conferences
Computational Structural Biology Conferences
Molecular Biology Conferences 2024
X-ray Crystallography Conferences
Bioinformatics Conferences
cryo-EM Conferences 2024
Cell Signalling Conferences
cryo-EM Conferences
Structural Biology Conferences 2024 Europe
Structural Biology Conferences 2024 USA
Bioinformatics Conferences 2024
Structural Bioinformatics Conferences
Protein Chemistry Conferences
Protein Engineering Conferences
Structural Biology Conferences
Tags
Protein Chemistry Conferences
cryo-EM Conferences
Structural Biology Conferences 2024 USA
Computational Structural Biology Conferences
Protein Engineering Conferences
Structural Genomics Conferences
Bioinformatics Conferences 2024
Proteomics Conferences 2024
Stereochemistry Conferences
cryo-EM Conferences 2024
Molecular Biology Conferences 2024
Structural Biology Conferences 2024
Structural Biology Conferences
NMR Spectroscopy Conferences
Molecular Biology Conferences
Tags
Structural Biology Conferences 2024 Europe
Stereochemistry Conferences
Structural Bioinformatics Conferences
Mass Spectrometry Conferences
Genomics Conferences
Molecular Biology Conferences
Computational Structural Biology Conferences
Molecular Biology Conferences 2024
Computational Structural Biology Conferences 2024
Bioinformatics Conferences 2024
Structural Biology Conferences 2024
cryo-EM Conferences 2024
Protein Chemistry Conferences
Cell Signalling Conferences
X-ray Crystallography Conferences
Tags
Protein Engineering Conferences
Structural Biology Conferences 2024 Europe
Genomics Conferences
Structural Biology Conferences 2024 USA
Protein Chemistry Conferences
Computational Structural Biology Conferences 2024
NMR Spectroscopy Conferences
Proteomics Conferences 2024
Bioinformatics Conferences
cryo-EM Conferences
Molecular Biology Conferences
Structural Bioinformatics Conferences
cryo-EM Conferences 2024
Proteomics Conferences
Computational Structural Biology Conferences
Tags
Structural Biology Conferences 2024 USA
cryo-EM Conferences 2024
NMR Spectroscopy Conferences
Bioinformatics Conferences
Proteomics Conferences 2024
Computational Structural Biology Conferences
Mass Spectrometry Conferences
Cell Signalling Conferences
Stereochemistry Conferences
Protein Engineering Conferences
Computational Structural Biology Conferences 2024
X-ray Crystallography Conferences
Structural Biology Conferences
Structural Biology Conferences 2024
Structural Genomics Conferences
Tags
Protein Engineering Conferences
Genomics Conferences
Mass Spectrometry Conferences
Proteomics Conferences 2024
X-ray Crystallography Conferences
Structural Biology Conferences 2024
Protein Chemistry Conferences
Structural Biology Conferences
Molecular Biology Conferences
Structural Bioinformatics Conferences
Computational Structural Biology Conferences
Cell Signalling Conferences
Structural Biology Conferences 2024 Europe
Stereochemistry Conferences
Structural Genomics Conferences
Tags
Structural Biology Conferences 2024 USA
Cell Signalling Conferences
Structural Biology Conferences
Bioinformatics Conferences 2024
Molecular Biology Conferences 2024
NMR Spectroscopy Conferences
Mass Spectrometry Conferences
cryo-EM Conferences 2024
Protein Engineering Conferences
Molecular Biology Conferences
cryo-EM Conferences
Structural Bioinformatics Conferences
Protein Chemistry Conferences
Proteomics Conferences
Structural Biology Conferences 2024
Tags
Computational Structural Biology Conferences 2024
Structural Bioinformatics Conferences
Molecular Biology Conferences 2024
cryo-EM Conferences 2024
Protein Engineering Conferences
Structural Biology Conferences
Stereochemistry Conferences
Protein Chemistry Conferences
Structural Biology Conferences 2024 Europe
Structural Biology Conferences 2024 USA
Cell Signalling Conferences
Bioinformatics Conferences
Structural Biology Conferences 2024
Bioinformatics Conferences 2024
Molecular Biology Conferences
Tags
Bioinformatics Conferences
cryo-EM Conferences 2024
Computational Structural Biology Conferences
Molecular Biology Conferences 2024
Cell Signalling Conferences
Protein Chemistry Conferences
Protein Engineering Conferences
Structural Biology Conferences 2024 USA
Structural Biology Conferences 2024
Stereochemistry Conferences
Structural Genomics Conferences
Proteomics Conferences
Genomics Conferences
Bioinformatics Conferences 2024
Structural Biology Conferences 2024 Europe
Tags
Protein Chemistry Conferences
X-ray Crystallography Conferences
Structural Biology Conferences
Protein Engineering Conferences
Bioinformatics Conferences
Protein Engineering Conferences
cryo-EM Conferences 2024
Structural Biology Conferences 2024 USA
Cell Signalling Conferences
Structural Bioinformatics Conferences
Proteomics Conferences 2024
Bioinformatics Conferences 2024
NMR Spectroscopy Conferences
Structural Biology Conferences 2024 Europe
Genomics Conferences
Tags
Molecular Biology Conferences 2024
Structural Biology Conferences 2024 Europe
cryo-EM Conferences 2024
Protein Engineering Conferences
Computational Structural Biology Conferences
Protein Engineering Conferences
Structural Biology Conferences 2024 USA
Proteomics Conferences
Genomics Conferences
Structural Biology Conferences 2024
Molecular Biology Conferences
Tags
Structural Bioinformatics Conferences
Protein Engineering Conferences
Protein Engineering Conferences
Mass Spectrometry Conferences
cryo-EM Conferences 2024
Genomics Conferences
X-ray Crystallography Conferences
Structural Biology Conferences 2024
Computational Structural Biology Conferences
Structural Biology Conferences
Molecular Biology Conferences 2024
Proteomics Conferences
Molecular Biology Conferences
NMR Spectroscopy Conferences
Stereochemistry Conferences
Tags
Structural Biology Conferences
Proteomics Conferences 2024
Protein Engineering Conferences
Structural Biology Conferences 2024 USA
Computational Structural Biology Conferences
Genomics Conferences
Mass Spectrometry Conferences
NMR Spectroscopy Conferences
Computational Structural Biology Conferences 2024
Structural Biology Conferences 2024 Europe
X-ray Crystallography Conferences
Structural Genomics Conferences
Tags
Molecular Biology Conferences 2024
Stereochemistry Conferences
cryo-EM Conferences
Genomics Conferences
Structural Biology Conferences 2024
cryo-EM Conferences 2024
X-ray Crystallography Conferences
Mass Spectrometry Conferences
Structural Biology Conferences 2024 USA
Protein Chemistry Conferences
Molecular Biology Conferences
Bioinformatics Conferences 2024
Proteomics Conferences
Protein Engineering Conferences
Structural Bioinformatics Conferences
Tags
Mass Spectrometry Conferences
Protein Engineering Conferences
Structural Bioinformatics Conferences
Genomics Conferences
Structural Biology Conferences 2024
NMR Spectroscopy Conferences
Structural Genomics Conferences
Computational Structural Biology Conferences 2024
Protein Engineering Conferences
Protein Chemistry Conferences
Structural Biology Conferences
Molecular Biology Conferences 2024
Computational Structural Biology Conferences
Cell Signalling Conferences
Bioinformatics Conferences 2024
Tags
NMR Spectroscopy Conferences
X-ray Crystallography Conferences
Stereochemistry Conferences
cryo-EM Conferences
Bioinformatics Conferences 2024
Structural Genomics Conferences
Molecular Biology Conferences 2024
Structural Biology Conferences 2024 USA
Protein Chemistry Conferences
Molecular Biology Conferences
Protein Engineering Conferences
Proteomics Conferences 2024
Structural Biology Conferences 2024 Europe
Cell Signalling Conferences
Proteomics Conferences
Tags
Molecular Biology Conferences
Proteomics Conferences
cryo-EM Conferences 2024
Molecular Biology Conferences 2024
Cell Signalling Conferences
Structural Genomics Conferences
cryo-EM Conferences
Computational Structural Biology Conferences 2024
Protein Engineering Conferences
X-ray Crystallography Conferences
Computational Structural Biology Conferences
Protein Engineering Conferences
NMR Spectroscopy Conferences
Structural Bioinformatics Conferences
Proteomics Conferences 2024
Tags
Structural Biology Conferences 2024 USA
Proteomics Conferences 2024
Structural Genomics Conferences
Protein Engineering Conferences
Structural Biology Conferences
Structural Biology Conferences 2024
X-ray Crystallography Conferences
Structural Biology Conferences 2024 Europe
Computational Structural Biology Conferences
Protein Chemistry Conferences
NMR Spectroscopy Conferences
Molecular Biology Conferences
Proteomics Conferences
Genomics Conferences
Molecular Biology Conferences 2024
Tags
Structural Biology Conferences 2024 USA
Structural Genomics Conferences
Computational Structural Biology Conferences
cryo-EM Conferences 2024
Computational Structural Biology Conferences 2024
X-ray Crystallography Conferences
Proteomics Conferences 2024
Structural Biology Conferences 2024 Europe
Bioinformatics Conferences 2024
Cell Signalling Conferences
Protein Chemistry Conferences
Bioinformatics Conferences
Protein Engineering Conferences
Proteomics Conferences
Structural Biology Conferences
Tags
Stereochemistry Conferences
Structural Biology Conferences 2024 USA
Protein Engineering Conferences
Protein Chemistry Conferences
Structural Biology Conferences
Molecular Biology Conferences 2024
Structural Genomics Conferences
cryo-EM Conferences
Structural Biology Conferences 2024
Structural Biology Conferences 2024 Europe
Protein Engineering Conferences
Structural Bioinformatics Conferences
Proteomics Conferences 2024
Mass Spectrometry Conferences
Genomics Conferences
Tags
Proteomics Conferences
Structural Biology Conferences 2024 USA
Structural Biology Conferences 2024
Protein Engineering Conferences
Structural Bioinformatics Conferences
Structural Genomics Conferences
cryo-EM Conferences 2024
Mass Spectrometry Conferences
Stereochemistry Conferences
Computational Structural Biology Conferences
Bioinformatics Conferences 2024
Molecular Biology Conferences
X-ray Crystallography Conferences
cryo-EM Conferences
Tags
Computational Structural Biology Conferences 2024
Genomics Conferences
Protein Engineering Conferences
cryo-EM Conferences
Protein Chemistry Conferences
X-ray Crystallography Conferences
Cell Signalling Conferences
Bioinformatics Conferences
Protein Engineering Conferences
Structural Biology Conferences 2024 USA
Structural Genomics Conferences
Structural Bioinformatics Conferences
Molecular Biology Conferences
Structural Biology Conferences
NMR Spectroscopy Conferences
Tags
Proteomics Conferences 2024
Bioinformatics Conferences
Protein Chemistry Conferences
Structural Genomics Conferences
Computational Structural Biology Conferences
Stereochemistry Conferences
NMR Spectroscopy Conferences
Molecular Biology Conferences
Molecular Biology Conferences 2024
X-ray Crystallography Conferences
Computational Structural Biology Conferences 2024
Structural Biology Conferences 2024
Protein Engineering Conferences
Structural Biology Conferences
cryo-EM Conferences
Tags
Proteomics Conferences 2024
Structural Biology Conferences
Stereochemistry Conferences
Protein Chemistry Conferences
Structural Genomics Conferences
Structural Biology Conferences 2024
Bioinformatics Conferences 2024
Molecular Biology Conferences
Computational Structural Biology Conferences
X-ray Crystallography Conferences
Computational Structural Biology Conferences 2024
Structural Biology Conferences 2024 USA
Genomics Conferences
cryo-EM Conferences
NMR Spectroscopy Conferences
Tags
Structural Genomics Conferences
Genomics Conferences
cryo-EM Conferences 2024
Proteomics Conferences
Structural Biology Conferences 2024
Molecular Biology Conferences 2024
Protein Engineering Conferences
Computational Structural Biology Conferences
Mass Spectrometry Conferences
Structural Biology Conferences
Protein Chemistry Conferences
Cell Signalling Conferences
Stereochemistry Conferences
Bioinformatics Conferences 2024
Structural Biology Conferences 2024 Europe
Tags
Proteomics Conferences
Protein Engineering Conferences
Computational Structural Biology Conferences 2024
cryo-EM Conferences
Proteomics Conferences 2024
Protein Chemistry Conferences
Protein Engineering Conferences
Molecular Biology Conferences 2024
Structural Biology Conferences 2024 Europe
Molecular Biology Conferences
NMR Spectroscopy Conferences
Cell Signalling Conferences
Mass Spectrometry Conferences
Structural Biology Conferences 2024
X-ray Crystallography Conferences
Tags
cryo-EM Conferences 2024
Mass Spectrometry Conferences
Structural Genomics Conferences
cryo-EM Conferences
Proteomics Conferences
Structural Biology Conferences 2024 USA
Molecular Biology Conferences
Bioinformatics Conferences
Protein Engineering Conferences
Genomics Conferences
Cell Signalling Conferences
Proteomics Conferences 2024
Bioinformatics Conferences 2024
Structural Biology Conferences 2024
Molecular Biology Conferences 2024
Tags
Structural Biology Conferences
Mass Spectrometry Conferences
Proteomics Conferences
Structural Bioinformatics Conferences
Stereochemistry Conferences
Proteomics Conferences 2024
Protein Engineering Conferences
Genomics Conferences
cryo-EM Conferences
NMR Spectroscopy Conferences
Computational Structural Biology Conferences
Molecular Biology Conferences 2024
Protein Chemistry Conferences
Computational Structural Biology Conferences 2024
cryo-EM Conferences 2024
Tags
Stereochemistry Conferences
Protein Engineering Conferences
Mass Spectrometry Conferences
NMR Spectroscopy Conferences
Structural Biology Conferences
Molecular Biology Conferences
Proteomics Conferences
Bioinformatics Conferences
Structural Biology Conferences 2024 Europe
Protein Engineering Conferences
Structural Biology Conferences 2024
Cell Signalling Conferences
Structural Bioinformatics Conferences
Protein Chemistry Conferences
Molecular Biology Conferences 2024
Tags
Genomics Conferences
Stereochemistry Conferences
Molecular Biology Conferences
Bioinformatics Conferences 2024
Protein Engineering Conferences
Bioinformatics Conferences
Computational Structural Biology Conferences 2024
Computational Structural Biology Conferences
Proteomics Conferences 2024
Structural Biology Conferences 2024 USA
cryo-EM Conferences 2024
Structural Biology Conferences 2024
Structural Bioinformatics Conferences
Structural Biology Conferences 2024 Europe
X-ray Crystallography Conferences
Tags
Structural Biology Conferences 2024 USA
Proteomics Conferences 2024
Structural Biology Conferences
Structural Biology Conferences 2024 Europe
Structural Genomics Conferences
Computational Structural Biology Conferences
Bioinformatics Conferences
cryo-EM Conferences
Genomics Conferences
Stereochemistry Conferences
Computational Structural Biology Conferences 2024
X-ray Crystallography Conferences
Protein Engineering Conferences
Structural Bioinformatics Conferences
Tags
Protein Chemistry Conferences
Mass Spectrometry Conferences
Molecular Biology Conferences
Protein Engineering Conferences
Structural Biology Conferences 2024
Stereochemistry Conferences
Structural Biology Conferences
Structural Biology Conferences 2024 Europe
Protein Engineering Conferences
Structural Biology Conferences 2024 USA
cryo-EM Conferences
Computational Structural Biology Conferences
Structural Bioinformatics Conferences
cryo-EM Conferences 2024
Computational Structural Biology Conferences 2024
Tags
Mass Spectrometry Conferences
NMR Spectroscopy Conferences
Computational Structural Biology Conferences
Protein Engineering Conferences
Proteomics Conferences
Structural Biology Conferences 2024 USA
Genomics Conferences
Structural Genomics Conferences
Structural Biology Conferences
Protein Chemistry Conferences
Bioinformatics Conferences 2024
Computational Structural Biology Conferences 2024
Structural Biology Conferences 2024
X-ray Crystallography Conferences
Cell Signalling Conferences
Tags
cryo-EM Conferences 2024
Protein Chemistry Conferences
Structural Bioinformatics Conferences
Structural Biology Conferences 2024
Structural Biology Conferences
Computational Structural Biology Conferences 2024
Structural Biology Conferences 2024 USA
Bioinformatics Conferences 2024
Genomics Conferences
Bioinformatics Conferences
Protein Engineering Conferences
Structural Biology Conferences 2024 Europe
Proteomics Conferences 2024
Stereochemistry Conferences
Cell Signalling Conferences
Tags
Computational Structural Biology Conferences 2024
Cell Signalling Conferences
Structural Biology Conferences 2024
Structural Biology Conferences
Bioinformatics Conferences 2024
Molecular Biology Conferences 2024
cryo-EM Conferences 2024
Mass Spectrometry Conferences
Bioinformatics Conferences
Structural Biology Conferences 2024 Europe
Computational Structural Biology Conferences
Protein Engineering Conferences
Structural Genomics Conferences
Structural Bioinformatics Conferences
Stereochemistry Conferences
There are several reasons why someone should attend an Internal Conference on Structural Biology and Biochemistry:
Networking Opportunities: Attending a conference provides an opportunity to network with other researchers, professionals, and experts in the field of structural biology and biochemistry. These networking opportunities can lead to collaborations, job opportunities, and future research collaborations.
Stay Updated on the Latest Research: Conferences provide a platform to learn about the latest research and advancements in the field of structural biology and biochemistry. Attendees can attend presentations and talks by leading experts in the field, which can help them stay up-to-date on the latest findings and trends.
Share Your Research: Conferences also provide an opportunity to present your own research and get feedback from peers and experts in the field. This can help you refine your research and improve its impact.
Professional Development: Conferences often include workshops and training sessions that can help attendees develop their skills and knowledge in the field of structural biology and biochemistry. These sessions can provide valuable training in specialized techniques and tools that can be applied to research.
Exposure to New Ideas: Conferences bring together researchers from different backgrounds and disciplines, which can lead to exposure to new ideas and approaches. This can help attendees develop new insights and perspectives on their own research and the field as a whole.
Market Insights of Structural Biology in USA:
The market value of Structural Biology in the USA is significant, as the country is home to some of the leading research institutions, pharmaceutical companies, and biotechnology firms in this field. According to a report by ResearchAndMarkets, the structural biology market in the USA was valued at USD 591.7 million in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 8.7% during the forecast period of 2021-2028.
The growth of the market in the USA is driven by factors such as the increasing prevalence of chronic diseases, rising demand for personalized medicine, and the growing adoption of structural biology techniques in drug discovery and development. In addition, the availability of government funding for research in this field is also contributing to the growth of the market.
The USA is home to some of the world's leading research institutions and universities, such as the National Institutes of Health (NIH), Harvard University, Stanford University, and the University of California, San Francisco (UCSF), among others. These institutions are conducting cutting-edge research in the field of Structural Biology, leading to new discoveries and breakthroughs in drug discovery and development.
Overall, the market value of Structural Biology in the USA is expected to continue to grow in the coming years, driven by factors such as technological advancements, increasing government funding, and rising demand for personalized medicine.
Market Insights of Structural Biology in Europe:
Structural Biology is a growing field in Europe, and it is contributing significantly to the region's research and innovation activities. According to a report by Allied Market Research, the European structural biology and molecular modeling market was valued at USD 839.45 million in 2020 and is projected to reach USD 1.21 billion by 2028, growing at a compound annual growth rate (CAGR) of 4.8% during the forecast period.
The growth of the market is driven by factors such as the increasing demand for new drug development, growing adoption of structural biology techniques in the biopharmaceutical industry, and advancements in technology. The region has a robust infrastructure for research and development, which is supporting the growth of the structural biology market.
The European Union is also actively investing in research and development activities related to structural biology through various initiatives and funding programs. For instance, the Horizon 2020 program has funded several projects related to structural biology and molecular modeling, with a focus on developing new therapies for a range of diseases.
In addition, many research institutions, academic centers, and biopharmaceutical companies are collaborating to develop new technologies and tools for structural biology research in Europe. This is leading to new discoveries and breakthroughs in the field, and is expected to further drive the growth of the market in the coming years.
Overall, the market value of Structural Biology in Europe is expected to continue to grow, driven by advancements in technology, increasing investment in research and development activities, and growing demand for new drug development in the biopharmaceutical industry.
Contact us now and we will make your event unique & unforgettable
mTORC1, the mammalian target of rapamycin complex 1, is a key regulator of cellular physiology. The lipid metabolite phosphatidic acid (PA) binds to and activates mTORC1 in response to nutrients and growth factors. After reviewing structural findings, we propose a model for PA activation of mTORC1. PA binds a highly conserved sequence on ?4 helix of the FKBP12-rapamycin binding domain of mTOR. It is proposed that PA binding to two adjacent positively charged amino acids breaks and shortens the C-terminal region of ?4-helix. This leads to profound consequences for substrate binding and catalytic activity of mTORC1.
The studies on the dendritic crystallization of biological solutions are significant for medical applications. This manuscript reports our systematic study on the solution dendritic crystallization as a function of temperature, pH value, and the concentrations of its major components. And the factors that cause the variation in the crystal patterns, the distribution of the main components in the crystals, and the sequence of their deposition or crystallization. By summarizing the general crystallization behaviour and formation mechanisms of biological solutions, we proposed the methods of crystal pattern analysis for the solution characteristics tests or growing the crystals with desired patterns for different purposes. By the methods, one can conduct a quantitative test on a solution by analysing its evaporated crystallization patterns. Therefore, the chemical compound measurements that usually need to use analytical instruments can be transferred to simple pattern recognition and analysis and make it become an objective test. With a smartphone-based portable imaging device, the crystal pattern analysis method can be a powerful means for daily use of medical and biochemical point-of-care testing (POCT). On this basis, we developed a simple smartphone-based salivary crystallization imaging system with functions of AI-aided rapid automatic pattern recognition and analysis to help pregnant women monitor their fetal status daily at home and predict their delivery date by analysing their saliva crystallization. The method combines the information of the fractal dimension with some specific forms of crystals in the salivary crystallization and estimates the delivery date in both quantitative and qualitative manners. The accuracy of the prediction was satisfactory, with 100% delivery in the predicted week, 93.3% within the three days, and 86.7% on the day as the prediction.
We present a new concept for crystallization of integral membrane proteins. Our working hypothesis relies on the assumption that by conjugating-micelles containing the target membrane protein, one would bring the latter into proximity and stabilize nucleation centers that would support crystal growth. Micellar conjugation is achieved with amphiphilic [metal:chelator] complexes generated at the micelle\water boundary. The binding affinity between the metal and the hydrophobic chelator used, defines the (i) strength of binding between: protein detergent complexes (PDCs) as well as (ii) the rate at which PDCs dissociate & reassociate until the most ordered PDCs assembly, is reached. Thus far, 3D crystals of two membrane proteins belonging to the retinal family were obtained via this approach, but these were either too small or too thin to allow structure determination. Therefore, His-tagged micelles are being developed as a potential alternative.